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Oral and gut microbial profiling in periodontitis and parkinson's disease
Yay, Ekin; Yılmaz, Melis; Toygar, Hilal; Balcı, Nur; Rivas, Carla Alvarez; Bolluk Kılıç, Başak; Zırh, Ali; Paster, Bruce J.; Kantarcı, Alpdoğan (Taylor & Francis Ltd, 2024)ObjectivesWe tested the hypothesis that Parkinson's disease (PA) alters the periodontitis-associated oral microbiome.MethodPatients with periodontitis with Parkinson's disease (PA+P) and without PA (P) and systemically and ... -
Parkinson's disease and the COVID-19 pandemic: Do quarantine affect the motor and non-motor symptoms of patients with and without deep brain stimulation?
Helvacı Yılmaz, Nesrin; Bolluk Kılıç, Başak; Zırh, Tahsin Ali; Aslan, Asile Seval; Hanoğlu, Lütfü (Galenos Publishing, 2022)Aim: Patients with chronic diseases were forced into lockdown due to the coronavirus disease-2019 pandemic. Extended quarantine could lead to physical inactivity and psychiatric problems. We investigated the effects of ... -
Parkinson's disease is positively associated with periodontal inflammation
Yılmaz, Melis; Yay, Ekin; Balcı, Nur; Toygar, Hilal; Bolluk Kılıç, Başak; Zırh, Ali; Rivas, Carla Alvarez; Kantarcı, Alpdoğan (Wiley, 2023)BackgroundParkinson's disease (PA) affects 1% of the global population above 60 years. PA pathogenesis involves severe neuroinflammation that impacts systemic and local inflammatory changes. We tested the hypothesis that ... -
Parkinson’s disease alters the composition of subgingival microbiome
Yay, Ekin; Yılmaz, Melis; Toygar, Hilal; Balcı, Nur; Alvarez Rivas, Carla; Bolluk Kılıç, Başak; Zırh, Ali; Paster, Bruce; Kantarcı, Alpdoğan (Taylor and Francis Ltd., 2023)Aim: The current study aimed to test the hypothesis that Parkinson’s disease exacerbates periodontitis by altering its microbiome. Materials and Methods: Clinical periodontal parameters were recorded. Subgingival samples ...